The application of adipose stem cells

April 27, 2020

THE APPLICATION OF ADIPOSE STEM CELLS

Kim, Y. J., &amp Jeong, J. H. (2014). Clinical application ofadipose stem cells in plastic surgery.&nbspJournal of Koreanmedical science,&nbsp29(4), 462-467.

Kim&amp Jeong (2014) focus their study on adipose stem cells (ASCs).They describe ASCs to share some features with normal mesenchyme stemcells. Since cell therapy is central to the modern regenerativemedicine, ASCs are important in facial plastic surgery. This articledescribes the clinical applications of adipose stem cells such as fatgrafting, wound healing, and local tissue ischemia recovery. Theinvestigators point out the limitation of the use of ASCs in plasticsurgery by the government. The article also discusses the future ofadipose stem cell uses.

Banyard, D. A., Salibian, A. A., Widgerow, A. D., &amp Evans, G. R.(2015). Implications for human adipose‐derivedstem cells in plastic surgery.&nbspJournal of cellular andmolecular medicine,&nbsp19(1), 21-30.

Thisarticle presents a systematic review of current adipose-derived stemcell isolation and identification. It discusses the available uses ofthis type of stem cell in plastic surgery, risks of its usage, andbarriers to translatability. The investigators provide informationfrom the latest research to find solutions to the obstacles. Banyard,Salibian, Widgerow &amp Evans (2015) argue that abundance of ADSCsand their accessibility in human tissue is responsible for thesignificant growth in the research field. This type of stem cell alsopossesses regenerative properties similar to other mesenchyme stemcells.

Gir, P., Oni, G., Brown, S. A., Mojallal, A., &amp Rohrich, R. J.(2012). Human adipose stem cells: current clinicalapplications.&nbspPlastic and reconstructive surgery,&nbsp129(6),1277-1290.

Thisarticle describes ADSCs as multipotent cells that have ease ofextraction from the adipose tissue and can expand in vitro. Thesecells have the ability to produce different cell types. Gir, Oni,Brown, Mojallal &amp Rohrich (2012) emphasize the need for safetyevaluation of ADSCs. The researchers use a systematic review strategyto examine published evidence and ongoing trials. The results of thestudy show significant positive outcomes in plastic surgery and otherfields. The article also discusses the disparities in the applicationof adipose-derive stem cells. The investigators suggest basicscientific, experimental, studies and randomized trials.

Salibian, A. A., Widgerow, A. D., Abrouk, M., &amp Evans, G. R.(2013). Stem cells in plastic surgery: a review of current clinicaland translational applications.&nbspArchives of plasticsurgery,&nbsp40(6), 666-675.

Salibian,Widgerow, Abrouk &amp Evans (2013) explored the characteristics ofstem cells include their self-renewal and differentiation properties.The regenerative techniques use these properties to treat tissuesdefects. The article discusses advancements and limitations ofavailable stem cell therapies. Topics such as the regeneration ofsoft tissues, cartilage, and peripheral nerves are covered in thereview. The study results present how ADSC transplants are effectivein treating defects associated with bony and soft tissues. Theinvestigators also address the application of ADSCs in aestheticsurgery. They make suggestions for future studies about stem cellsand plastic surgery.

Trojahn Kølle, S. F., Oliveri, R. S., Glovinski, P. V., Elberg, J.J., Fischer-Nielsen, A., &amp Drzewiecki, K. T. (2012). Importanceof mesenchymal stem cells in autologous fat grafting: a systematicreview of existing studies.&nbspJournal of plastic surgery andhand surgery,&nbsp46(2), 59-68.

Thisarticle discusses the application of autologous fat grafting inrepairing and augmenting soft tissues. The advantages anddisadvantages of autologous fat grafting are discussed in detail.This article explains how ADSCs can be used use to enrich fat grantto overcome the disadvantages. The investigators outline the outcomesof high-level enrichment of fat grafts with ADSCs. They also describethe surgical and tissue handling techniques guarantee the success andsafety of lipo-filling.

Mizuno, H., Tobita, M., &amp Uysal, A. C. (2012). Concise review:adipose‐derived stem cellsas a novel tool for future regenerative medicine.&nbspStemcells,&nbsp30(5), 804-810.

Mizuno,Tobita &amp Uysal (2012) conducted an investigation to explore thebiological background of ASCs, differentiation capabilities, currentpreclinical and clinical data regarding their application inregenerative medicine. They discuss the therapeutic interventionsthat employ adipose stem cells to treat various diseases. The articlecovers the reasons why the focus has shifted from embryonic stemcells to mesenchymal stem cells. The investigators provide theexplanations why adipose stem cells are ideal types of stem cells.They are easily harvested from the adipose tissue. Outcomes ofvarious studies on the properties and application of ASCs areexplained. The article suggests future directions of cell-basedtherapy and regenerative medicine.

References

Gir, P., Oni, G., Brown, S. A., Mojallal, A., &amp Rohrich, R. J.(2012). Human adipose stem cells: current clinicalapplications.&nbspPlastic and reconstructive surgery,&nbsp129(6),1277-1290.

Kim, Y. J., &amp Jeong, J. H. (2014). Clinical application ofadipose stem cells in plastic surgery.&nbspJournal of Koreanmedical science,&nbsp29(4), 462-467.

Mizuno, H., Tobita, M., &amp Uysal, A. C. (2012). Concise review:adipose‐derived stem cellsas a novel tool for future regenerative medicine.&nbspStemcells,&nbsp30(5), 804-810.

The application of adipose stem cells

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